Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer’s disease model
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چکیده
منابع مشابه
Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer’s disease model
Several lines of evidence suggest that neuregulin 1 (NRG1) signaling may influence cognitive function and neuropathology in Alzheimer's disease (AD). To test this possibility, full-length type I or type III NRG1 was overexpressed via lentiviral vectors in the hippocampus of line 41 AD mouse. Both type I and type III NRG1 improves deficits in the Morris water-maze behavioral task. Neuropathology...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep31692